Part of Highway 104 in Merland, Antigonish County was closed for a time last night.
RCMP say around 6 p.m. officers were alerted of an empty tractor trailer came to rest on its side, covering both lanes.
The driver and lone occupant of the vehicle, a 56-year-old New Brunswick man, suffered minor injuries and was transported to hospital via EHS.
Investigators believe high winds in the area were a factor in the crash.